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Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult β-thalassemia major

Minihepcidins are hepcidin agonists that have been previously shown to reverse iron overload and improve erythropoiesis in mice affected by non-transfusion-dependent thalassemia. Given the extreme anemia that occurred with the previous model of transfusion-dependent thalassemia, that model was inade...

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Détails bibliographiques
Publié dans:Haematologica
Auteurs principaux: Casu, Carla, Chessa, Roberta, Liu, Alison, Gupta, Ritama, Drakesmith, Hal, Fleming, Robert, Ginzburg, Yelena Z., MacDonald, Brian, Rivella, Stefano
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327634/
https://ncbi.nlm.nih.gov/pubmed/31582543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.212589
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