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β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

β-thalassemia is a disease characterized by anemia and is associated with ineffective erythropoiesis and iron dysregulation resulting in iron overload. The peptide hormone hepcidin regulates iron metabolism, and insufficient hepcidin synthesis is responsible for iron overload in minimally transfused...

詳細記述

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書誌詳細
主要な著者: Ginzburg, Yelena, Rivella, Stefano
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204905/
https://ncbi.nlm.nih.gov/pubmed/21768301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-283614
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