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β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

β-thalassemia is a disease characterized by anemia and is associated with ineffective erythropoiesis and iron dysregulation resulting in iron overload. The peptide hormone hepcidin regulates iron metabolism, and insufficient hepcidin synthesis is responsible for iron overload in minimally transfused...

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Bibliografske podrobnosti
Main Authors: Ginzburg, Yelena, Rivella, Stefano
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204905/
https://ncbi.nlm.nih.gov/pubmed/21768301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-283614
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