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β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

β-thalassemia is a disease characterized by anemia and is associated with ineffective erythropoiesis and iron dysregulation resulting in iron overload. The peptide hormone hepcidin regulates iron metabolism, and insufficient hepcidin synthesis is responsible for iron overload in minimally transfused...

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Detalhes bibliográficos
Main Authors: Ginzburg, Yelena, Rivella, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204905/
https://ncbi.nlm.nih.gov/pubmed/21768301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-283614
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