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β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

β-thalassemia is a disease characterized by anemia and is associated with ineffective erythropoiesis and iron dysregulation resulting in iron overload. The peptide hormone hepcidin regulates iron metabolism, and insufficient hepcidin synthesis is responsible for iron overload in minimally transfused...

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Bibliografiske detaljer
Main Authors: Ginzburg, Yelena, Rivella, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204905/
https://ncbi.nlm.nih.gov/pubmed/21768301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-283614
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