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Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult β-thalassemia major

Minihepcidins are hepcidin agonists that have been previously shown to reverse iron overload and improve erythropoiesis in mice affected by non-transfusion-dependent thalassemia. Given the extreme anemia that occurred with the previous model of transfusion-dependent thalassemia, that model was inade...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Casu, Carla, Chessa, Roberta, Liu, Alison, Gupta, Ritama, Drakesmith, Hal, Fleming, Robert, Ginzburg, Yelena Z., MacDonald, Brian, Rivella, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327634/
https://ncbi.nlm.nih.gov/pubmed/31582543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.212589
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