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The role of ineffective erythropoiesis in non-transfusion-dependent thalassemia
Ineffective erythropoiesis is the hallmark of beta-thalassemia that triggers a cascade of compensatory mechanisms resulting in clinical sequelae such as erythroid marrow expansion, extramedullary hematopoiesis, splenomegaly, and increased gastrointestinal iron absorption. Recent studies have begun t...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697110/ https://ncbi.nlm.nih.gov/pubmed/22631035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0268-960X(12)70005-X |
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