Endoplasmic Reticulum Stress in Subepithelial Myofibroblasts Increases the TGF-β1 Activity That Regulates Fibrosis in Crohn’s Disease

BACKGROUND: Endoplasmic reticulum (ER) stress is an essential response of epithelial and immune cells to inflammation in Crohn’s disease. The presence and mechanisms that might regulate the ER stress response in subepithelial myofibroblasts (SEMFs) and its role in the development of fibrosis in pati...

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Bibliografische gegevens
Gepubliceerd in:Inflamm Bowel Dis
Hoofdauteurs: Li, Chao, Grider, John R, Murthy, Karnam S, Bohl, Jaime, Rivet, Emily, Wieghard, Nicole, Kuemmerle, John F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Basic Science Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324000/
https://ncbi.nlm.nih.gov/pubmed/32031621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izaa015
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