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Vargas: heuristic-free alignment for assessing linear and graph read aligners

MOTIVATION: Read alignment is central to many aspects of modern genomics. Most aligners use heuristics to accelerate processing, but these heuristics can fail to find the optimal alignments of reads. Alignment accuracy is typically measured through simulated reads; however, the simulated location ma...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Darby, Charlotte A, Gaddipati, Ravi, Schatz, Michael C, Langmead, Ben
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320598/
https://ncbi.nlm.nih.gov/pubmed/32321164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa265
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