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Vargas: heuristic-free alignment for assessing linear and graph read aligners

MOTIVATION: Read alignment is central to many aspects of modern genomics. Most aligners use heuristics to accelerate processing, but these heuristics can fail to find the optimal alignments of reads. Alignment accuracy is typically measured through simulated reads; however, the simulated location ma...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Darby, Charlotte A, Gaddipati, Ravi, Schatz, Michael C, Langmead, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320598/
https://ncbi.nlm.nih.gov/pubmed/32321164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa265
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