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Vargas: heuristic-free alignment for assessing linear and graph read aligners

MOTIVATION: Read alignment is central to many aspects of modern genomics. Most aligners use heuristics to accelerate processing, but these heuristics can fail to find the optimal alignments of reads. Alignment accuracy is typically measured through simulated reads; however, the simulated location ma...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Bioinformatics
Päätekijät: Darby, Charlotte A, Gaddipati, Ravi, Schatz, Michael C, Langmead, Ben
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320598/
https://ncbi.nlm.nih.gov/pubmed/32321164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa265
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