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Vargas: heuristic-free alignment for assessing linear and graph read aligners

MOTIVATION: Read alignment is central to many aspects of modern genomics. Most aligners use heuristics to accelerate processing, but these heuristics can fail to find the optimal alignments of reads. Alignment accuracy is typically measured through simulated reads; however, the simulated location ma...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Darby, Charlotte A, Gaddipati, Ravi, Schatz, Michael C, Langmead, Ben
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320598/
https://ncbi.nlm.nih.gov/pubmed/32321164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa265
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