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Vargas: heuristic-free alignment for assessing linear and graph read aligners

MOTIVATION: Read alignment is central to many aspects of modern genomics. Most aligners use heuristics to accelerate processing, but these heuristics can fail to find the optimal alignments of reads. Alignment accuracy is typically measured through simulated reads; however, the simulated location ma...

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Detaylı Bibliyografya
Yayımlandı:Bioinformatics
Asıl Yazarlar: Darby, Charlotte A, Gaddipati, Ravi, Schatz, Michael C, Langmead, Ben
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320598/
https://ncbi.nlm.nih.gov/pubmed/32321164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa265
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