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First‐in‐human study with ACT‐539313, a novel selective orexin‐1 receptor antagonist

AIMS: The orexin system is involved in anxiety behaviour and corresponding physiological reactions and constitutes a target for treatment of anxiety disorders. ACT‐539313 is a potent, selective orexin‐1 receptor antagonist being developed for the treatment of anxiety disorders. This first‐in‐human s...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Kaufmann, Priska, Ort, Marion, Golor, Georg, Kornberger, Rüdiger, Dingemanse, Jasper
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319015/
https://ncbi.nlm.nih.gov/pubmed/32067262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14251
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