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Treatment of Rare Inflammatory Kidney Diseases: Drugs Targeting the Terminal Complement Pathway

The complement system comprises the frontline of the innate immune system. Triggered by pathogenic surface patterns in different pathways, the cascade concludes with the formation of a membrane attack complex (MAC; complement components C5b to C9) and C5a, a potent anaphylatoxin that elicits various...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Anliker-Ort, Marion, Dingemanse, Jasper, van den Anker, John, Kaufmann, Priska
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758461/
https://ncbi.nlm.nih.gov/pubmed/33362783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.599417
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