Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model

BACKGROUND: Extracellular vesicles produced by bone marrow mesenchymal stem cells (BMSC-EVs) can play important roles in the repair of injured tissues. Though numerous studies have reported the effect of EVs on renal fibrosis, the underlying mechanisms remain unclear. We hypothesized that BMSC-EVs c...

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Detaylı Bibliyografya
Yayımlandı:Stem Cell Res Ther
Asıl Yazarlar: Shi, Zhengzhou, Wang, Qi, Zhang, Youbo, Jiang, Dapeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318505/
https://ncbi.nlm.nih.gov/pubmed/32586368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01767-8
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