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Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model

BACKGROUND: Extracellular vesicles produced by bone marrow mesenchymal stem cells (BMSC-EVs) can play important roles in the repair of injured tissues. Though numerous studies have reported the effect of EVs on renal fibrosis, the underlying mechanisms remain unclear. We hypothesized that BMSC-EVs c...

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Библиографические подробности
Опубликовано в: :Stem Cell Res Ther
Главные авторы: Shi, Zhengzhou, Wang, Qi, Zhang, Youbo, Jiang, Dapeng
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318505/
https://ncbi.nlm.nih.gov/pubmed/32586368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01767-8
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