Involvement of RhoA/ROCK in myocardial fibrosis in a rat model of type 2 diabetes

AIM: To investigate whether activation of RhoA/Rho kinase (ROCK) is involved in myocardial fibrosis in diabetic hearts. METHODS: A rat model of type 2 diabetes was established using high fat diet combined with streptozotocin (30 mg/kg, ip). Animals were randomly divided into 3 groups: control rats,...

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Autores principales: Zhou, Hong, Li, Yong-jun, Wang, Mian, Zhang, Li-hui, Guo, Bing-yan, Zhao, Zhan-sheng, Meng, Feng-ling, Deng, Yong-gui, Wang, Rui-ying
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002528/
https://ncbi.nlm.nih.gov/pubmed/21743486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.54
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