Population Pharmacokinetics of Piperacillin following Continuous Infusion in Critically Ill Patients and Impact of Renal Function on Target Attainment

Pharmacokinetic changes are often seen in patients with severe infections. Administration by continuous infusion has been suggested to optimize antibiotic exposure and pharmacokinetic/pharmacodynamic (PK/PD) target attainment for β-lactams. In an observational study, unbound piperacillin concentrati...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Klastrup, Vibeke, Thorsted, Anders, Storgaard, Merete, Christensen, Steffen, Friberg, Lena E., Öbrink-Hansen, Kristina
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Clinical Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318020/
https://ncbi.nlm.nih.gov/pubmed/32284376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02556-19
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