Population pharmacokinetics of piperacillin in febrile children receiving cancer chemotherapy: the impact of body weight and target on an optimal dosing regimen

BACKGROUND: The β-lactam antibiotic piperacillin (in combination with tazobactam) is commonly chosen for empirical treatment of suspected bacterial infections. However, pharmacokinetic variability among patient populations and across ages leads to uncertainty when selecting a dosing regimen to achie...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Antimicrob Chemother
Egile Nagusiak: Thorsted, Anders, Kristoffersson, Anders N, Maarbjerg, Sabine F, Schrøder, Henrik, Wang, Mikala, Brock, Birgitte, Nielsen, Elisabet I, Friberg, Lena E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916132/
https://ncbi.nlm.nih.gov/pubmed/31273375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz270
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