Loading...

Population Pharmacokinetics of Piperacillin following Continuous Infusion in Critically Ill Patients and Impact of Renal Function on Target Attainment

Pharmacokinetic changes are often seen in patients with severe infections. Administration by continuous infusion has been suggested to optimize antibiotic exposure and pharmacokinetic/pharmacodynamic (PK/PD) target attainment for β-lactams. In an observational study, unbound piperacillin concentrati...

Full description

Saved in:
Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Klastrup, Vibeke, Thorsted, Anders, Storgaard, Merete, Christensen, Steffen, Friberg, Lena E., Öbrink-Hansen, Kristina
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318020/
https://ncbi.nlm.nih.gov/pubmed/32284376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02556-19
Tags: Add Tag
No Tags, Be the first to tag this record!