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Population Pharmacokinetics of Piperacillin following Continuous Infusion in Critically Ill Patients and Impact of Renal Function on Target Attainment

Pharmacokinetic changes are often seen in patients with severe infections. Administration by continuous infusion has been suggested to optimize antibiotic exposure and pharmacokinetic/pharmacodynamic (PK/PD) target attainment for β-lactams. In an observational study, unbound piperacillin concentrati...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Klastrup, Vibeke, Thorsted, Anders, Storgaard, Merete, Christensen, Steffen, Friberg, Lena E., Öbrink-Hansen, Kristina
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318020/
https://ncbi.nlm.nih.gov/pubmed/32284376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02556-19
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