Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections

Elimination of pulmonary Pseudomonas aeruginosa (PA) infections is challenging to accomplish with antibiotic therapies, mainly due to resistance mechanisms. Quorum sensing inhibitors (QSIs) interfering with biofilm formation can thus complement antibiotics. For simultaneous and improved delivery of...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Ho, Duy‐Khiet, Murgia, Xabier, De Rossi, Chiara, Christmann, Rebekka, Hüfner de Mello Martins, Antonio G., Koch, Marcus, Andreas, Anastasia, Herrmann, Jennifer, Müller, Rolf, Empting, Martin, Hartmann, Rolf W., Desmaele, Didier, Loretz, Brigitta, Couvreur, Patrick, Lehr, Claus‐Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317969/
https://ncbi.nlm.nih.gov/pubmed/32243047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202001407
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