Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections

Elimination of pulmonary Pseudomonas aeruginosa (PA) infections is challenging to accomplish with antibiotic therapies, mainly due to resistance mechanisms. Quorum sensing inhibitors (QSIs) interfering with biofilm formation can thus complement antibiotics. For simultaneous and improved delivery of...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Ho, Duy‐Khiet, Murgia, Xabier, De Rossi, Chiara, Christmann, Rebekka, Hüfner de Mello Martins, Antonio G., Koch, Marcus, Andreas, Anastasia, Herrmann, Jennifer, Müller, Rolf, Empting, Martin, Hartmann, Rolf W., Desmaele, Didier, Loretz, Brigitta, Couvreur, Patrick, Lehr, Claus‐Michael
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317969/
https://ncbi.nlm.nih.gov/pubmed/32243047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202001407
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires