A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms

Pseudomonas aeruginosa (PA) infections can be notoriously difficult to treat and are often accompanied by the development of antimicrobial resistance (AMR). Quorum sensing inhibitors (QSI) acting on PqsR (MvfR) – a crucial transcriptional regulator serving major functions in PA virulence – can enhan...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Adv Sci (Weinh)
Κύριοι συγγραφείς: Schütz, Christian, Ho, Duy‐Khiet, Hamed, Mostafa Mohamed, Abdelsamie, Ahmed Saad, Röhrig, Teresa, Herr, Christian, Kany, Andreas Martin, Rox, Katharina, Schmelz, Stefan, Siebenbürger, Lorenz, Wirth, Marius, Börger, Carsten, Yahiaoui, Samir, Bals, Robert, Scrima, Andrea, Blankenfeldt, Wulf, Horstmann, Justus Constantin, Christmann, Rebekka, Murgia, Xabier, Koch, Marcus, Berwanger, Aylin, Loretz, Brigitta, Hirsch, Anna Katharina Herta, Hartmann, Rolf Wolfgang, Lehr, Claus‐Michael, Empting, Martin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2021
Θέματα:
Full Papers
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224453/
https://ncbi.nlm.nih.gov/pubmed/34165899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202004369
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