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Tofacitinib Loaded Squalenyl Nanoparticles for Targeted Follicular Delivery in Inflammatory Skin Diseases

Tofacitinib (TFB), a Janus kinase inhibitor, has shown excellent success off-label in treating various dermatological diseases, especially alopecia areata (AA). However, TFB’s safe and targeted delivery into hair follicles (HFs) is highly desirable due to its systemic adverse effects. Nanoparticles...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Christmann, Rebekka, Ho, Duy-Khiet, Wilzopolski, Jenny, Lee, Sangeun, Koch, Marcus, Loretz, Brigitta, Vogt, Thomas, Bäumer, Wolfgang, Schaefer, Ulrich F., Lehr, Claus-Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760822/
https://ncbi.nlm.nih.gov/pubmed/33255225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121131
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