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Immune responses in beta-thalassaemia: heme oxygenase 1 reduces cytokine production and bactericidal activity of human leucocytes

Patients with beta-thalassaemia increase the risk of bacterial infections, particularly Burkholderia pseudomallei (Bp), the causative agent of melioidosis in Thailand. Impaired immune cell functions may be the cause of this susceptibility, but detailed mechanisms have not been defined. In this study...

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Publicado en:Sci Rep
Autores principales: Nithichanon, Arnone, Tussakhon, Inthira, Samer, Waraporn, Kewcharoenwong, Chidchamai, Ato, Manabu, Bancroft, Gregory J., Lertmemongkolchai, Ganjana
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314746/
https://ncbi.nlm.nih.gov/pubmed/32581238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67346-2
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