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Immune responses in beta-thalassaemia: heme oxygenase 1 reduces cytokine production and bactericidal activity of human leucocytes

Patients with beta-thalassaemia increase the risk of bacterial infections, particularly Burkholderia pseudomallei (Bp), the causative agent of melioidosis in Thailand. Impaired immune cell functions may be the cause of this susceptibility, but detailed mechanisms have not been defined. In this study...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Nithichanon, Arnone, Tussakhon, Inthira, Samer, Waraporn, Kewcharoenwong, Chidchamai, Ato, Manabu, Bancroft, Gregory J., Lertmemongkolchai, Ganjana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314746/
https://ncbi.nlm.nih.gov/pubmed/32581238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67346-2
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