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Immune responses in beta-thalassaemia: heme oxygenase 1 reduces cytokine production and bactericidal activity of human leucocytes

Patients with beta-thalassaemia increase the risk of bacterial infections, particularly Burkholderia pseudomallei (Bp), the causative agent of melioidosis in Thailand. Impaired immune cell functions may be the cause of this susceptibility, but detailed mechanisms have not been defined. In this study...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nithichanon, Arnone, Tussakhon, Inthira, Samer, Waraporn, Kewcharoenwong, Chidchamai, Ato, Manabu, Bancroft, Gregory J., Lertmemongkolchai, Ganjana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314746/
https://ncbi.nlm.nih.gov/pubmed/32581238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67346-2
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