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Immune responses in beta-thalassaemia: heme oxygenase 1 reduces cytokine production and bactericidal activity of human leucocytes

Patients with beta-thalassaemia increase the risk of bacterial infections, particularly Burkholderia pseudomallei (Bp), the causative agent of melioidosis in Thailand. Impaired immune cell functions may be the cause of this susceptibility, but detailed mechanisms have not been defined. In this study...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Nithichanon, Arnone, Tussakhon, Inthira, Samer, Waraporn, Kewcharoenwong, Chidchamai, Ato, Manabu, Bancroft, Gregory J., Lertmemongkolchai, Ganjana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314746/
https://ncbi.nlm.nih.gov/pubmed/32581238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67346-2
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