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Glibenclamide reduces pro-inflammatory cytokine production by neutrophils of diabetes patients in response to bacterial infection

Type 2 diabetes mellitus is a major risk factor for melioidosis, which is caused by Burkholderia pseudomallei. Our previous study has shown that polymorphonuclear neutrophils (PMNs) from diabetic subjects exhibited decreased functions in response to B. pseudomallei. Here we investigated the mechanis...

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Detalhes bibliográficos
Main Authors: Kewcharoenwong, Chidchamai, Rinchai, Darawan, Utispan, Kusumawadee, Suwannasaen, Duangchan, Bancroft, Gregory J., Ato, Manabu, Lertmemongkolchai, Ganjana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842541/
https://ncbi.nlm.nih.gov/pubmed/24285369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03363
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