Interleukin 10 inhibits pro-inflammatory cytokine responses and killing of Burkholderia pseudomallei

Melioidosis, caused by Burkholderia pseudomallei, is endemic in northeastern Thailand and Northern Australia. Severe septicemic melioidosis is associated with high levels of pro-inflammatory cytokines and is correlated with poor clinical outcomes. IL-10 is an immunoregulatory cytokine, which in othe...

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Udgivet i:Sci Rep
Main Authors: Kessler, Bianca, Rinchai, Darawan, Kewcharoenwong, Chidchamai, Nithichanon, Arnone, Biggart, Rachael, Hawrylowicz, Catherine M., Bancroft, Gregory J., Lertmemongkolchai, Ganjana
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316963/
https://ncbi.nlm.nih.gov/pubmed/28216665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42791
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