A dopamine-induced gene expression signature regulates neuronal function and cocaine response

Drugs of abuse elevate dopamine levels in the nucleus accumbens (NAc) and alter transcriptional programs believed to promote long-lasting synaptic and behavioral adaptations. Here, we leveraged single-nucleus RNA-sequencing to generate a comprehensive molecular atlas of cell subtypes in the NAc, def...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Savell, Katherine E., Tuscher, Jennifer J., Zipperly, Morgan E., Duke, Corey G., Phillips, Robert A., Bauman, Allison J., Thukral, Saakshi, Sultan, Faraz A., Goska, Nicholas A., Ianov, Lara, Day, Jeremy J.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314536/
https://ncbi.nlm.nih.gov/pubmed/32637607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba4221
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