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Regulation of dopamine-dependent transcription and cocaine action by Gadd45b

Exposure to drugs of abuse produces robust transcriptional and epigenetic reorganization within brain reward circuits that outlives the direct effects of the drug and may contribute to addiction. DNA methylation is a covalent epigenetic modification that is altered following stimulant exposure and i...

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Publicat a:Neuropsychopharmacology
Autors principals: Zipperly, Morgan E., Sultan, Faraz A., Graham, Guan-En, Brane, Andrew C., Simpkins, Natalie A., Carullo, Nancy V. N., Ianov, Lara, Day, Jeremy J.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027017/
https://ncbi.nlm.nih.gov/pubmed/32927466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-00828-z
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