Eosinophil-derived IL-13 Promotes Emphysema

The inflammatory responses in chronic airway diseases leading to emphysema are not fully defined. We hypothesized that lung eosinophilia contributes to airspace enlargement in a mouse model, and emphysema in patients with COPD. A transgenic mouse model of chronic type 2 pulmonary inflammation (I5/hE...

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Detalhes bibliográficos
Publicado no:Eur Respir J
Main Authors: Doyle, Alfred D., Mukherjee, Manali, LeSuer, William E., Bittner, Tyler B., Pasha, Saif M., Frere, Justin J., Neely, Joseph L., Kloeber, Jake A., Shim, Kelly P., Ochkur, Sergei I., Ho, Terence, Svenningsen, Sarah, Wright, Benjamin L., Rank, Matthew A., Lee, James J., Nair, Parameswaran, Jacobsen, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7313423/
https://ncbi.nlm.nih.gov/pubmed/30728205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01291-2018
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