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Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation

Rationale: The release of eosinophil granule proteins in the lungs of patients with asthma has been dogmatically linked with lung remodeling and airway hyperresponsiveness. However, the demonstrated inability of established mouse models to display the eosinophil degranulation occurring in human subj...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Jacobsen, Elizabeth A., Ochkur, Sergei I., Doyle, Alfred D., LeSuer, William E., Li, Wen, Protheroe, Cheryl A., Colbert, Dana, Zellner, Katie R., Shen, HuaHao H., Irvin, Charles G., Lee, James J., Lee, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443899/
https://ncbi.nlm.nih.gov/pubmed/27922744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201606-1129OC
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