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Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice

Eosinophil activities are often linked with allergic diseases such as asthma and the pathologies accompanying helminth infection. These activities have been hypothesized to be mediated, in part, by the release of cationic proteins stored in the secondary granules of these granulocytes. The majority...

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Detalhes bibliográficos
Main Authors: Doyle, Alfred D., Jacobsen, Elizabeth A., Ochkur, Sergei I., McGarry, Michael P., Shim, Kevin G., Nguyen, David T. C., Protheroe, Cheryl, Colbert, Dana, Kloeber, Jake, Neely, Joseph, Shim, Kelly P., Dyer, Kimberly D., Rosenberg, Helene F., Lee, James J., Lee, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731932/
https://ncbi.nlm.nih.gov/pubmed/23736699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-473405
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