Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils

Eosinophils are generally linked to innate host defense against helminths, as well as the pathologies associated with allergic diseases, such as asthma. Nonetheless, the activities of eosinophils remain poorly understood, which in turn, has prevented detailed definitions of their role(s) in health a...

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Autors principals: Doyle, Alfred D., Jacobsen, Elizabeth A., Ochkur, Sergei I., Willetts, Lian, Shim, Kelly, Neely, Joseph, Kloeber, Jake, LeSuer, Will E., Pero, Ralph S., Lacy, Paige, Moqbel, Redwan, Lee, Nancy A., Lee, James J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2013
Matèries:
Spotlight on Leading Edge Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685019/
https://ncbi.nlm.nih.gov/pubmed/23630390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0213089
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