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Impact of eosinophil-peroxidase (EPX) deficiency on eosinophil structure and function in mouse airways

Eosinophil-peroxidase (EPX) is a major constituent of the large cytoplasmic granules of both human and mouse eosinophilic leukocytes. Human EPX-deficiency is a rare, autosomal-recessive disorder limited to the eosinophil lineage. Our intent was to explore the impact of EPX gene-deletion on eosinophi...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Percopo, Caroline M., Krumholz, Julia O., Fischer, Elizabeth R., Kraemer, Laura S., Ma, Michelle, Laky, Karen, Rosenberg, Helene F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310085/
https://ncbi.nlm.nih.gov/pubmed/30285291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3AB0318-090RR
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