Eosinophil-derived IL-13 Promotes Emphysema

The inflammatory responses in chronic airway diseases leading to emphysema are not fully defined. We hypothesized that lung eosinophilia contributes to airspace enlargement in a mouse model, and emphysema in patients with COPD. A transgenic mouse model of chronic type 2 pulmonary inflammation (I5/hE...

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Bibliografski detalji
Izdano u:Eur Respir J
Glavni autori: Doyle, Alfred D., Mukherjee, Manali, LeSuer, William E., Bittner, Tyler B., Pasha, Saif M., Frere, Justin J., Neely, Joseph L., Kloeber, Jake A., Shim, Kelly P., Ochkur, Sergei I., Ho, Terence, Svenningsen, Sarah, Wright, Benjamin L., Rank, Matthew A., Lee, James J., Nair, Parameswaran, Jacobsen, Elizabeth A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7313423/
https://ncbi.nlm.nih.gov/pubmed/30728205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01291-2018
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