Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction

The lysis of red blood cells was shown to occur in human ruptured atherosclerotic lesions and intraventricular hemorrhage (IVH) of the brain. Liberated cell-free hemoglobin was found to undergo oxidation in both pathologies. We hypothesize that hemoglobin-derived peptides are generated during hemogl...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Lab Invest
Egile Nagusiak: Posta, Niké, Csősz, Éva, Oros, Melinda, Pethő, Dávid, Potor, László, Kalló, Gergő, Hendrik, Zoltán, Sikura, Katalin Éva, Méhes, Gábor, Tóth, Csaba, Posta, József, Balla, György, Balla, József
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group US 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311325/
https://ncbi.nlm.nih.gov/pubmed/32054994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-020-0403-x
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