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Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease

BACKGROUND AND PURPOSE: Calcification of heart valves is a frequent pathological finding in chronic kidney disease and in elderly patients. Hydrogen sulfide (H(2)S) may exert anti‐calcific actions. Here we investigated H(2)S as an inhibitor of valvular calcification and to identify its targets in th...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Sikura, Katalin Éva, Potor, László, Szerafin, Tamás, Oros, Melinda, Nagy, Péter, Méhes, Gábor, Hendrik, Zoltán, Zarjou, Abolfazl, Agarwal, Anupam, Posta, Niké, Torregrossa, Roberta, Whiteman, Matthew, Fürtös, Ibolya, Balla, György, Balla, József
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024713/
https://ncbi.nlm.nih.gov/pubmed/31017307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14691
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