Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization

INTRODUCTION: Hydrogen sulfide (H(2)S) was revealed to inhibit aortic valve calcification and inflammation was implicated in the pathogenesis of calcific aortic valve disease (CAVD). OBJECTIVES: We investigate whether H(2)S inhibits mineralization via abolishing inflammation. METHODS AND RESULTS: Ex...

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Pubblicato in:J Adv Res
Autori principali: Éva Sikura, Katalin, Combi, Zsolt, Potor, László, Szerafin, Tamás, Hendrik, Zoltán, Méhes, Gábor, Gergely, Péter, Whiteman, Matthew, Beke, Lívia, Fürtös, Ibolya, Balla, György, Balla, József
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7728582/
https://ncbi.nlm.nih.gov/pubmed/33318875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2020.07.005
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