The Fungal Iron Chelator Desferricoprogen Inhibits Atherosclerotic Plaque Formation

Hemoglobin, heme and iron are implicated in the progression of atherosclerosis. Therefore, we investigated whether the hydrophobic fungal iron chelator siderophore, desferricoprogen (DFC) inhibits atherosclerosis. DFC reduced atherosclerotic plaque formation in ApoE(−/−) mice on an atherogenic diet....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Potor, László, Sikura, Katalin Éva, Hegedűs, Hajnalka, Pethő, Dávid, Szabó, Zsuzsa, Szigeti, Zsuzsa M, Pócsi, István, Trencsényi, György, Szikra, Dezső, Garai, Ildikó, Gáll, Tamás, Combi, Zsolt, Kappelmayer, János, Balla, György, Balla, József
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369830/
https://ncbi.nlm.nih.gov/pubmed/32635347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134746
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