The Fungal Iron Chelator Desferricoprogen Inhibits Atherosclerotic Plaque Formation

Hemoglobin, heme and iron are implicated in the progression of atherosclerosis. Therefore, we investigated whether the hydrophobic fungal iron chelator siderophore, desferricoprogen (DFC) inhibits atherosclerosis. DFC reduced atherosclerotic plaque formation in ApoE(−/−) mice on an atherogenic diet....

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出版年:Int J Mol Sci
主要な著者: Potor, László, Sikura, Katalin Éva, Hegedűs, Hajnalka, Pethő, Dávid, Szabó, Zsuzsa, Szigeti, Zsuzsa M, Pócsi, István, Trencsényi, György, Szikra, Dezső, Garai, Ildikó, Gáll, Tamás, Combi, Zsolt, Kappelmayer, János, Balla, György, Balla, József
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369830/
https://ncbi.nlm.nih.gov/pubmed/32635347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134746
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