The Fungal Iron Chelator Desferricoprogen Inhibits Atherosclerotic Plaque Formation

Hemoglobin, heme and iron are implicated in the progression of atherosclerosis. Therefore, we investigated whether the hydrophobic fungal iron chelator siderophore, desferricoprogen (DFC) inhibits atherosclerosis. DFC reduced atherosclerotic plaque formation in ApoE(−/−) mice on an atherogenic diet....

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Potor, László, Sikura, Katalin Éva, Hegedűs, Hajnalka, Pethő, Dávid, Szabó, Zsuzsa, Szigeti, Zsuzsa M, Pócsi, István, Trencsényi, György, Szikra, Dezső, Garai, Ildikó, Gáll, Tamás, Combi, Zsolt, Kappelmayer, János, Balla, György, Balla, József
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369830/
https://ncbi.nlm.nih.gov/pubmed/32635347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134746
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