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Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression
Hemorrhage and hemolysis with subsequent heme release are implicated in many pathologies. Endothelial cells (ECs) encounter large amount of free heme after hemolysis and are at risk of damage from exogenous heme. Here we show that hemorrhage aggravates endoplasmic reticulum (ER) stress in human caro...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8129109/ https://ncbi.nlm.nih.gov/pubmed/34001932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89713-3 |
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