Ferryl Hemoglobin and Heme Induce A(1)-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation

Infiltration of red blood cells into atheromatous plaques and oxidation of hemoglobin (Hb) and lipoproteins are implicated in the pathogenesis of atherosclerosis. α(1)-microglobulin (A1M) is a radical-scavenging and heme-binding protein. In this work, we examined the origin and role of A1M in human...

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Pubblicato in:Int J Mol Sci
Autori principali: Pethő, Dávid, Gáll, Tamás, Hendrik, Zoltán, Nagy, Annamária, Beke, Lívia, Gergely, Attila Péter, Méhes, Gábor, Tóth, Csaba, Gram, Magnus, Åkerström, Bo, Balla, György, Balla, József
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268598/
https://ncbi.nlm.nih.gov/pubmed/34206377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136668
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