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Ferryl Hemoglobin and Heme Induce A(1)-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation

Infiltration of red blood cells into atheromatous plaques and oxidation of hemoglobin (Hb) and lipoproteins are implicated in the pathogenesis of atherosclerosis. α(1)-microglobulin (A1M) is a radical-scavenging and heme-binding protein. In this work, we examined the origin and role of A1M in human...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pethő, Dávid, Gáll, Tamás, Hendrik, Zoltán, Nagy, Annamária, Beke, Lívia, Gergely, Attila Péter, Méhes, Gábor, Tóth, Csaba, Gram, Magnus, Åkerström, Bo, Balla, György, Balla, József
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268598/
https://ncbi.nlm.nih.gov/pubmed/34206377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136668
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