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Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation
Class I PI3K enzymes are critical for the maintenance of effective immunity. In T cells, PI3Kα and PI3Kδ are activated by the TCR and costimulatory receptors, whereas PI3Kγ is activated by G protein–coupled chemokine receptors. PI3Kδ is a key regulator of regulatory T (Treg) cell function. PI3K isof...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AAI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7311201/ https://ncbi.nlm.nih.gov/pubmed/32414808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000043 |
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