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Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells

BACKGROUND: Aberrant hedgehog (HH) signaling is implicated in the development of various cancer entities such as medulloblastoma. Activation of GLI transcription factors was revealed as the driving force upon pathway activation. Increased phosphorylation of essential effectors such as Smoothened (SM...

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發表在:Cell Commun Signal
Main Authors: Scheidt, Tamara, Alka, Oliver, Gonczarowska-Jorge, Humberto, Gruber, Wolfgang, Rathje, Florian, Dell’Aica, Margherita, Rurik, Marc, Kohlbacher, Oliver, Zahedi, René P., Aberger, Fritz, Huber, Christian G.
格式: Artigo
語言:Inglês
出版: BioMed Central 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310537/
https://ncbi.nlm.nih.gov/pubmed/32576205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00591-0
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