Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells

BACKGROUND: Aberrant hedgehog (HH) signaling is implicated in the development of various cancer entities such as medulloblastoma. Activation of GLI transcription factors was revealed as the driving force upon pathway activation. Increased phosphorylation of essential effectors such as Smoothened (SM...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Commun Signal
Autori principali: Scheidt, Tamara, Alka, Oliver, Gonczarowska-Jorge, Humberto, Gruber, Wolfgang, Rathje, Florian, Dell’Aica, Margherita, Rurik, Marc, Kohlbacher, Oliver, Zahedi, René P., Aberger, Fritz, Huber, Christian G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310537/
https://ncbi.nlm.nih.gov/pubmed/32576205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00591-0
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