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Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells

BACKGROUND: Aberrant hedgehog (HH) signaling is implicated in the development of various cancer entities such as medulloblastoma. Activation of GLI transcription factors was revealed as the driving force upon pathway activation. Increased phosphorylation of essential effectors such as Smoothened (SM...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Scheidt, Tamara, Alka, Oliver, Gonczarowska-Jorge, Humberto, Gruber, Wolfgang, Rathje, Florian, Dell’Aica, Margherita, Rurik, Marc, Kohlbacher, Oliver, Zahedi, René P., Aberger, Fritz, Huber, Christian G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310537/
https://ncbi.nlm.nih.gov/pubmed/32576205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00591-0
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