Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses

HIV-1 envelope (Env) trimers, stabilized in a prefusion-closed conformation, can elicit humoral responses capable of neutralizing HIV-1 strains closely matched in sequence to the immunizing strain. One strategy to increase elicited neutralization breadth involves vaccine priming of immune responses...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Chuang, Gwo-Yu, Lai, Yen-Ting, Boyington, Jeffrey C., Cheng, Cheng, Geng, Hui, Narpala, Sandeep, Rawi, Reda, Schmidt, Stephen D., Tsybovsky, Yaroslav, Verardi, Raffaello, Xu, Kai, Yang, Yongping, Zhang, Baoshan, Chambers, Michael, Changela, Anita, Corrigan, Angela R., Kong, Rui, Olia, Adam S., Ou, Li, Sarfo, Edward K., Wang, Shuishu, Wu, Winston, Doria-Rose, Nicole A., McDermott, Adrian B., Mascola, John R., Kwong, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307166/
https://ncbi.nlm.nih.gov/pubmed/32295908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00074-20
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky