MYC protein stability is negatively regulated by BRD4

The protooncogene MYC regulates a variety of cellular processes, including proliferation and metabolism. Maintaining MYC at homeostatic levels is critical to normal cell function; overexpression drives many cancers. MYC stability is regulated through phosphorylation: phosphorylation at Thr58 signals...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Devaiah, Ballachanda N., Mu, Jie, Akman, Ben, Uppal, Sheetal, Weissman, Jocelyn D., Cheng, Dan, Baranello, Laura, Nie, Zuqin, Levens, David, Singer, Dinah S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306749/
https://ncbi.nlm.nih.gov/pubmed/32482868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919507117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados