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CIITA and Its Dual Roles in MHC Gene Transcription
Class II transactivator (CIITA) is a transcriptional coactivator that regulates γ-interferon-activated transcription of Major Histocompatibility Complex (MHC) class I and II genes. As such, it plays a critical role in immune responses: CIITA deficiency results in aberrant MHC gene expression and con...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868913/ https://ncbi.nlm.nih.gov/pubmed/24391648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00476 |
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