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Two faces of BRD4: Mitotic bookmark and transcriptional lynchpin
The bromodomain protein BRD4 links cell cycle and transcription, bookmarking active genes during mitosis and serving as a scaffold for transcription factors. Our recent discovery that BRD4 is a RNA Polymerase II CTD kinase identifies a novel transcriptional function. Here we discuss our model in the...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644036/ https://ncbi.nlm.nih.gov/pubmed/23131666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.22542 |
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