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Two faces of BRD4: Mitotic bookmark and transcriptional lynchpin

The bromodomain protein BRD4 links cell cycle and transcription, bookmarking active genes during mitosis and serving as a scaffold for transcription factors. Our recent discovery that BRD4 is a RNA Polymerase II CTD kinase identifies a novel transcriptional function. Here we discuss our model in the...

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Sonraí Bibleagrafaíochta
Main Authors: Devaiah, Ballachanda N., Singer, Dinah S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644036/
https://ncbi.nlm.nih.gov/pubmed/23131666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.22542
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