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BRD4 is a Histone Acetyltransferase that Evicts Nucleosomes from Chromatin
Bromodomain protein 4 (BRD4) is a chromatin-binding protein implicated in cancer and autoimmune diseases that functions as a scaffold for transcription factors at promoters and super-enhancers. Whereas chromatin de-compaction and transcriptional activation of target genes are associated with BRD4 bi...
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| Опубликовано в: : | Nat Struct Mol Biol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899182/ https://ncbi.nlm.nih.gov/pubmed/27159561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3228 |
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